The big hit from the album was "Whip It," which reached #14 on the singles chart. The strange western/new wave video of that song also received a ton of airplay on MTV. However, many critics, including your humble author, favored "Girl U Want" -- a song that is somehow both mechanical and rocking.
"Girl U Want" was inspired by the Knack's "My Sharona," although in typical Devo style, it is about unrequited love; the lyrics contrasting with the uptempo melody. As to the video ... I still have no idea what it means. But it is definitely interesting.
More interesting stuff: Devo created a mellowish alternate version of this song around 1982 that is worth checking out. Additionally, both Robert Palmer and Soundgarden covered the song, and had (unsurprisingly) really different interpretations. All three of the above covers are on YouTube, and I highly recommend a listen.